Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.6
USERS' SCORE
Moderately Good
Based on 14 Reviews
7
Supplement Facts
Serving Size: 2 Veggie Capsules
Amount Per Serving
%DV
BioCell Collagen®(from chicken sternal cartilage) providing minimum:Hydrolyzed Collagen Type IIChondroitin SulfateHyaluronic Acid
1000 mg600 mg200 mg100 mg
††††
Top Medical Research Studies
3
No additional benefits from HA injections
We examined whether adding hyaluronic acid (HA) injections to physical therapy (PT) could improve outcomes for patients with frozen shoulder. In a well-structured study, 70 participants were divided into two groups—with one receiving HA injections alongside PT, while the other focused solely on PT.
After assessing their shoulder movement, pain, and quality of life, we found no significant extra benefits from the HA injections. This suggests that continuing with just PT could be a more cost-effective approach for managing this condition.
After assessing their shoulder movement, pain, and quality of life, we found no significant extra benefits from the HA injections. This suggests that continuing with just PT could be a more cost-effective approach for managing this condition.
Read More
8
We investigated how ultrasound-guided hyaluronic acid injections perform against steroid injections in treating frozen shoulder, specifically looking at pain relief and improved range of motion.
In a randomized trial with 100 participants, we treated groups either with a steroid injection or hyaluronic acid combined with capsular distension.
Both treatments proved effective, but we found that the hyaluronic acid approach particularly boosted passive external rotation more than steroids alone.
This suggests a promising option for managing this challenging condition.
In a randomized trial with 100 participants, we treated groups either with a steroid injection or hyaluronic acid combined with capsular distension.
Both treatments proved effective, but we found that the hyaluronic acid approach particularly boosted passive external rotation more than steroids alone.
This suggests a promising option for managing this challenging condition.
Read More
7
We conducted a systematic review and meta-analysis to investigate how effective hyaluronic acid (HA) injections are compared to corticosteroid (CS) injections for addressing frozen shoulder, or adhesive capsulitis.
We analyzed seven studies out of over ten thousand articles. Our findings indicate that while CS injections may provide quicker pain relief, HA injections show similar effectiveness after six to twelve weeks.
Therefore, HA could be a good option for patients needing multiple injections or looking for a treatment with fewer side effects.
We analyzed seven studies out of over ten thousand articles. Our findings indicate that while CS injections may provide quicker pain relief, HA injections show similar effectiveness after six to twelve weeks.
Therefore, HA could be a good option for patients needing multiple injections or looking for a treatment with fewer side effects.
Read More
Most Useful Reviews
9
Shoulder pain gone
1 people found this helpful
Hyaluronic acid earns a 5+ on the Timur scale from me. After a month of use, my shoulder joint stopped hurting. I'm now able to train 100%. I highly recommend it.
Read More
9
Disappearance of pain
After 4 weeks on this product, my shoulder pain vanished. I even discontinued my anti-inflammatory medication. I recommend it to anyone suffering from joint pain.
Read More
9
Quick improvement noted
After just a week of taking this product, my shoulder joint stopped hurting. The tablets are easy to swallow and highly effective.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 16 Researches
6.6
- All Researches
9
We explored the effectiveness of intra-articular injections combining hyaluronic acid and tramadol in treating adhesive capsulitis, commonly known as frozen shoulder.
We compared this approach to hyaluronic acid injections alone among thirty patients. The results showed that patients receiving both treatments experienced faster pain relief without adverse effects.
However, the study also suggests that while the combination therapy is beneficial, it does not indicate a significant overall improvement over hyaluronic acid alone.
We compared this approach to hyaluronic acid injections alone among thirty patients. The results showed that patients receiving both treatments experienced faster pain relief without adverse effects.
However, the study also suggests that while the combination therapy is beneficial, it does not indicate a significant overall improvement over hyaluronic acid alone.
Read More
8
We explored the effectiveness of a new injectable hydrogel combining hyaluronic acid and pluronic F-127 to treat frozen shoulder, a condition that causes joint stiffness due to inflammation.
Our study revealed that this hydrogel, loaded with dexamethasone and collagenase, significantly improved joint mobility compared to traditional medication alone. The hydrogel was designed to release its drugs steadily for about 10 days, which helps break down excessive collagen that limits movement.
Overall, our findings highlight the potential of this combined hydrogel therapy as a promising option for individuals dealing with frozen shoulder.
Our study revealed that this hydrogel, loaded with dexamethasone and collagenase, significantly improved joint mobility compared to traditional medication alone. The hydrogel was designed to release its drugs steadily for about 10 days, which helps break down excessive collagen that limits movement.
Overall, our findings highlight the potential of this combined hydrogel therapy as a promising option for individuals dealing with frozen shoulder.
Read More
8
Hyaluronic acid enhances treatment outcomes
We assessed the impact of combining ultrasound-guided hydrodilatation with hyaluronic acid and physical therapy versus physical therapy alone on patients with frozen shoulder.
In a well-structured study involving 62 participants, half received the combined treatment while the other half followed just physical therapy.
Results showed that the group receiving the hyaluronic acid along with physical therapy experienced additional benefits, suggesting this combination could enhance recovery up to 12 weeks post-treatment.
In a well-structured study involving 62 participants, half received the combined treatment while the other half followed just physical therapy.
Results showed that the group receiving the hyaluronic acid along with physical therapy experienced additional benefits, suggesting this combination could enhance recovery up to 12 weeks post-treatment.
Read More
8
We investigated how ultrasound-guided hyaluronic acid injections perform against steroid injections in treating frozen shoulder, specifically looking at pain relief and improved range of motion.
In a randomized trial with 100 participants, we treated groups either with a steroid injection or hyaluronic acid combined with capsular distension.
Both treatments proved effective, but we found that the hyaluronic acid approach particularly boosted passive external rotation more than steroids alone.
This suggests a promising option for managing this challenging condition.
In a randomized trial with 100 participants, we treated groups either with a steroid injection or hyaluronic acid combined with capsular distension.
Both treatments proved effective, but we found that the hyaluronic acid approach particularly boosted passive external rotation more than steroids alone.
This suggests a promising option for managing this challenging condition.
Read More
8
We assessed the effectiveness of hyaluronic acid treatment for frozen shoulder in a study involving 87 patients. Each participant had severe pain and limited movement, with some receiving hyaluronic acid injections prior to surgery.
After arthroscopic capsular release, we observed that improvements in shoulder function correlated with the severity of tendon adhesions. While all patients exhibited enhanced movement and strength post-surgery, hyaluronic acid's specific benefit remains unclear. Ultimately, it appears while some treatments help, hyaluronic acid may not have played a significant role.
After arthroscopic capsular release, we observed that improvements in shoulder function correlated with the severity of tendon adhesions. While all patients exhibited enhanced movement and strength post-surgery, hyaluronic acid's specific benefit remains unclear. Ultimately, it appears while some treatments help, hyaluronic acid may not have played a significant role.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 14 Reviews
7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Shoulder pain gone
1 people found this helpful
Hyaluronic acid earns a 5+ on the Timur scale from me. After a month of use, my shoulder joint stopped hurting. I'm now able to train 100%. I highly recommend it.
Read More
9
Disappearance of pain
After 4 weeks on this product, my shoulder pain vanished. I even discontinued my anti-inflammatory medication. I recommend it to anyone suffering from joint pain.
Read More
9
Quick improvement noted
After just a week of taking this product, my shoulder joint stopped hurting. The tablets are easy to swallow and highly effective.
Read More
9
Easier shoulder movement
Good. My frozen shoulders have become much easier. It seems to work for me.
Read More
7.5
Comfort restored
3 people found this helpful
I've noticed an effect! Initially sceptical of dietary supplements, I avoided drugs with many contraindications. After three weeks of this medication, my shoulder joints are much more comfortable, and there’s no more finger crunching. I haven’t felt this good in ages and will continue taking it.
Read More
Frequently Asked Questions
9
Quick improvement noted
After just a week of taking this product, my shoulder joint stopped hurting. The tablets are easy to swallow and highly effective.
9
Disappearance of pain
After 4 weeks on this product, my shoulder pain vanished. I even discontinued my anti-inflammatory medication. I recommend it to anyone suffering from joint pain.
7.5
Effective pain relief
1 people found this helpful
I tried this product based on a positive review. I experienced pain in my knees, hips, elbows, and shoulders, making it hard to walk, but after a week, the pain was alleviated, and I truly felt it helped.
7.5
Scepticism waned
Initially, I was concerned about pain in my knee and shoulder joints, doubting any change was possible. However, after completing a 3-month course, my opinion changed dramatically; the discomfort in my joints has disappeared, though I did not notice a change in my skin.
9
Shoulder pain gone
1 people found this helpful
Hyaluronic acid earns a 5+ on the Timur scale from me. After a month of use, my shoulder joint stopped hurting. I'm now able to train 100%. I highly recommend it.
9
Easier shoulder movement
Good. My frozen shoulders have become much easier. It seems to work for me.
0
Worsened shoulder condition
16 people found this helpful
Unfortunately, I found hyaluronic acid to be ineffective. Instead of improvement, my right shoulder now crunches and aches continuously after starting this supplement. I suspect it may be an allergic reaction, as my condition worsened.
7.5
Good product overall
1 people found this helpful
I purchased this product searching for relief from my shoulder pain. I believe chondroitin and hyaluronic acid supplements can substantially aid in healing your shoulder. It's genuinely a good product.
7.5
Shoulder tear improvement
I believe this helped me with my shoulder tear, likely from years of heavy bench pressing. However, it's essential to take additional supplements, like fish oil, for better results.
7.5
Post-surgery aid
An excellent remedy for strengthening joints, I used it after shoulder surgery. It significantly assisted in the faster regeneration of tissue and joints.
7
We conducted a systematic review and meta-analysis to investigate how effective hyaluronic acid (HA) injections are compared to corticosteroid (CS) injections for addressing frozen shoulder, or adhesive capsulitis.
We analyzed seven studies out of over ten thousand articles. Our findings indicate that while CS injections may provide quicker pain relief, HA injections show similar effectiveness after six to twelve weeks.
Therefore, HA could be a good option for patients needing multiple injections or looking for a treatment with fewer side effects.
We analyzed seven studies out of over ten thousand articles. Our findings indicate that while CS injections may provide quicker pain relief, HA injections show similar effectiveness after six to twelve weeks.
Therefore, HA could be a good option for patients needing multiple injections or looking for a treatment with fewer side effects.
7
We explored the use of hyaluronic acid (HA) injections for treating adhesive capsulitis, commonly known as frozen shoulder. The systematic review analyzed seven studies, comparing HA outcomes with traditional treatment methods.
We observed significant improvements in range of motion and pain relief in patients using HA. Interestingly, when compared to cortisone injections, HA delivered similar results. However, the variety of treatments in the studies made it challenging to draw solid conclusions.
While HA may not directly determine final outcomes, it could support early mobilization during the painful initial phases of frozen shoulder, helping prevent prolonged immobility.
We observed significant improvements in range of motion and pain relief in patients using HA. Interestingly, when compared to cortisone injections, HA delivered similar results. However, the variety of treatments in the studies made it challenging to draw solid conclusions.
While HA may not directly determine final outcomes, it could support early mobilization during the painful initial phases of frozen shoulder, helping prevent prolonged immobility.
8
We aimed to assess how well a combination treatment of hyaluronic acid and a corticosteroid helps people with frozen shoulder. In our study of 30 participants, we found that those receiving the combined injections showed notable improvements in pain and shoulder movement after six months.
The hyaluronic acid treatment seems to enhance outcomes, likely due to its effects on joint tissue and fluid management. While both treatment groups experienced benefits, the combination therapy proved to be particularly effective for healing adhesive capsulitis.
The hyaluronic acid treatment seems to enhance outcomes, likely due to its effects on joint tissue and fluid management. While both treatment groups experienced benefits, the combination therapy proved to be particularly effective for healing adhesive capsulitis.
3
No additional benefits from HA injections
We examined whether adding hyaluronic acid (HA) injections to physical therapy (PT) could improve outcomes for patients with frozen shoulder. In a well-structured study, 70 participants were divided into two groups—with one receiving HA injections alongside PT, while the other focused solely on PT.
After assessing their shoulder movement, pain, and quality of life, we found no significant extra benefits from the HA injections. This suggests that continuing with just PT could be a more cost-effective approach for managing this condition.
After assessing their shoulder movement, pain, and quality of life, we found no significant extra benefits from the HA injections. This suggests that continuing with just PT could be a more cost-effective approach for managing this condition.
References
- Wang Z, Shen M, Wu S. Efficacy comparison of sodium hyaluronate, corticosteroids, and autologous platelet-rich plasma in the treatment of primary frozen shoulder. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024;49:1271. 10.11817/j.issn.1672-7347.2024.240219
- Uhm KE, Chang MC. Comparison of Effectiveness of Intraarticular Hyaluronate and Corticosteroid injections in Adhesive Capsulitis: A Systematic Review and Meta-analysis. Pain Physician. 2024;27:387.
- Zhang J, Song Y, Zhu L, You Y, Hu J, et al. An injectable thermosensitive hyaluronic acid/pluronic F-127 hydrogel for deep penetration and combination therapy of frozen shoulder. Int J Biol Macromol. 2024;263:130342. 10.1016/j.ijbiomac.2024.130342
- Wu SY, Hsu PC, Tsai YY, Huang JR, Wang KA, et al. Efficacy of combined ultrasound-guided hydrodilatation with hyaluronic acid and physical therapy in patients with adhesive capsulitis: A randomised controlled trial. Clin Rehabil. 2024;38:202. 10.1177/02692155231200089
- Ahn Y, Moon YS, Park GY, Cho SC, Lee YJ, et al. Efficacy of Intra-articular Triamcinolone and Hyaluronic Acid in a Frozen Shoulder Rat Model. Am J Sports Med. 2023;51:2881. 10.1177/03635465231188524
- Mao B, Peng R, Zhang Z, Zhang K, Li J, et al. The Effect of Intra-articular Injection of Hyaluronic Acid in Frozen Shoulder: a Systematic Review and Meta-analysis of Randomized Controlled Trials. J Orthop Surg Res. 2022;17:128. 10.1186/s13018-022-03017-4
- Akhtar M, Nadeem RDA, Shah Gillani SF, Cheema OI, Nadeem MR. Comparison of intra articular NSAID (ketorolac) injection versus hyaluronic acid injection for the mean decrease of pain score (according to UCLA shoulder rating scale) in the management of adhesive capsulitis. Pak J Pharm Sci. 2019;32:953.
- Papalia R, Tecame A, Vadalà G, Russo F, Perna M, et al. The use of hyaluronic acid in the treatment of shoulder capsulitis: a systematic review. J Biol Regul Homeost Agents. 2017;31:23.
- Kim KH, Suh JW, Oh KY. The effect of intra-articular hyaluronate and tramadol injection on patients with adhesive capsulitis of the shoulder. J Back Musculoskelet Rehabil. 2017;30:913. 10.3233/BMR-160641
- Lim TK, Koh KH, Shon MS, Lee SW, Park YE, et al. Intra-articular injection of hyaluronate versus corticosteroid in adhesive capsulitis. Orthopedics. 2014;37:e860. 10.3928/01477447-20140924-51
- Park KD, Nam HS, Lee JK, Kim YJ, Park Y. Treatment effects of ultrasound-guided capsular distension with hyaluronic acid in adhesive capsulitis of the shoulder. Arch Phys Med Rehabil. 2013;94:264. 10.1016/j.apmr.2012.10.002
- Hsieh LF, Hsu WC, Lin YJ, Chang HL, Chen CC, et al. Addition of intra-articular hyaluronate injection to physical therapy program produces no extra benefits in patients with adhesive capsulitis of the shoulder: a randomized controlled trial. Arch Phys Med Rehabil. 2012;93:957. 10.1016/j.apmr.2012.01.021
- Kanbe K, Inoue K, Inoue Y. Dynamic movement of the long head of the biceps tendon in frozen shoulders. J Orthop Surg (Hong Kong). 2008;16:295.
- Calis M, Demir H, Ulker S, Kirnap M, Duygulu F, et al. Is intraarticular sodium hyaluronate injection an alternative treatment in patients with adhesive capsulitis?. Rheumatol Int. 2006;26:536.
- Tamai K, Mashitori H, Ohno W, Hamada J, Sakai H, et al. Synovial response to intraarticular injections of hyaluronate in frozen shoulder: a quantitative assessment with dynamic magnetic resonance imaging. J Orthop Sci. 2004;9:230.
- Rovetta G, Monteforte P. Intraarticular injection of sodium hyaluronate plus steroid versus steroid in adhesive capsulitis of the shoulder. Int J Tissue React. 1998;20:125.
